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Daily Report : Biotech stocks show a historic level of internal selling pressure

Jason Goepfert
2021-12-16
Many biotechnology stocks have been sold aggressively in the past few months. Breadth indicators on a custom biotech index shows that internal selling is on par with some of the worst declines in 22 years. There is decent evidence that it's enough to suggest washed-out conditions.
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Biotech stocks show a historic level of internal selling pressure: Many biotechnology stocks have been sold aggressively in the past few months. Breadth indicators on a custom biotech index shows that internal selling is on par with some of the worst declines in 22 years. There is decent evidence that it's enough to suggest washed-out conditions.

Bottom Line:

STOCKS: Hold

Sentiment hit a pessimistic extreme by early December and then buyers showed enough interest to trigger a thrust in breadth. Those are reliable precursors to higher prices. There is a lot of disagreement among sectors, though, with negative divergences in tech but impressive participation in sectors like consumer staples. We should work higher but it's a bifurcated market.

BONDS: Hold

Despite mostly steady prices, investors turned pessimistic on bonds to a nearly decade-high degree by late November. Sentiment has recovered since then, which has been a mostly positive sign over the past 20 years, but not necessarily prior to then.

GOLD: Hold
Gold and miners were rejected after trying to recover above their 200-day averages in May. Some oversold extremes in breadth measures among miners triggered in late September, and they rebounded strongly then gave those gains back. Still not much of an apparent edge here.

Smart / Dumb Money Confidence

Smart Money Confidence: 61% Dumb Money Confidence: 34%

Risk Levels

Stocks Short-Term

Stocks Medium-Term

Bonds

Crude Oil

Gold

Agriculture

Research

Biotech stocks show a historic level of internal selling pressure

By Jason Goepfert

BOTTOM LINE
Many biotechnology stocks have been sold aggressively in the past few months. Breadth indicators on a custom biotech index shows that internal selling is on par with some of the worst declines in 22 years. There is decent evidence that it's enough to suggest washed-out conditions.

FORECAST / TIMEFRAME
IBB -- Up, Long-Term

Key points:

  • A custom index of Biotechnology stocks shows severe internal selling pressure
  • Several metrics are showing readings on par with the worst declines in 22 years
  • Initial recoveries following severely oversold readings led to mostly higher long-term returns

Bio-techs have been bio-wrecks

Heading into February's speculative peak, almost everything was in gear. That euphoric sentiment eased as some of the riskiest parts of the markets took a dive or treaded water at best.

Since then, there have been entire sectors that have lagged the broader market. Some equity indexes, especially those weighted by market capitalization, are at or near record highs. But not everyone is enjoying the gains.

As the Wall Street Journal recently noted:

"Biotech stocks have fallen to earth with a thud in 2021 after soaring last year amid excitement over the development of Covid-19 vaccines, dealing big losses to some hedge funds...

The SPDR S&P Biotech ETF (XBI), an equal-weighted index of biotech stocks, has fallen about 22% so far this year through Friday, and is down 37% from its Feb. 8 peak. The ETF has tumbled nearly 9% since Thanksgiving. Biotech has performed worse than all 11 S&P 500 sectors this year, a time when the broader index has notched a total gain of nearly 21%."

Getting reliable information on the losses in the sector is difficult. It's a notoriously volatile group, with share prices skyrocketing based on rumors or collapsing and de-listing based on the same. That can trigger heavy turnover in Biotechnology indexes, with historical studies often suffering from survivorship bias.

Looking at Biotech destruction under the surface

Using Portfolio123, we can create metrics that look at the breadth of the performance among many of these stocks to gauge whether recent declines are enough to suggest the worst is likely over. We've done our best to recreate the stocks included in the ICE Biotechnology Index, the index underlying the largest Biotech fund, IBB. There are a little over 300 stocks in the custom index, but it is not perfect.

There is some evidence that the selling pressure is overdone. At the recent low, fewer than 10% of these stocks traded above their 10-day moving averages. That ranks in the bottom 2% of all days since 1999.

Fewer than 15% of them traded above their 50-day averages, ranking in the bottom 3% of all days.

Fewer than 20% of them held above their long-term 200-day moving averages, in the bottom 4% of all days.

Fewer than 10% of Biotech stocks were able to hold within 20% of their 52-week highs, ranking in the bottom 1% of all days in the past 22 years.

Fewer than 20% of the stocks outperformed a broad Biotech index, ranking in the bottom 1% of all days.

The median stock in this sector got hammered, with a drawdown of more than 50% from its 52-week high. That's in the bottom 2% of all readings.

Combining all these metrics into a composite, it recently dipped below 20%, recording a level of oversold behavior in the bottom 1% of all days.

The stocks have recovered a bit since then. The composite has risen above 20% and held there for more than a week, suggesting the worst of the selling pressure could be behind.

Other times the composite did this, it was usually the case that the sector was washed out. The most significant risk is a cluster of these signals in 2002 and 2016 as they whipped back and forth. Long-term returns were still decent, but early buyers got some heartburn.

What the research tells us...

Biotech stocks are a tough group for traders and even tougher for investors. They can go years with little reward, punctuated by the occasional panic due to a regulatory move or alarming study outcome. Despite a year of miraculous advances, many of these stocks have not only been overlooked but sold aggressively. 

The selling pressure heading into this week was on par with some of the worst internal declines in 22 years. While it's always a risk to rely only on historical precedents, especially in the shorter term (witness Chinese tech stocks), there is some decent evidence that long-term returns in the sector should be positive.


Active Studies

Click here to view the Active Research on the site.
Time FrameBullishBearish
Short-Term23
Medium-Term142
Long-Term168

Indicators at Extremes

Click here to view on the site (% Extremes and "Excess" tabs on the dashboard).
% Showing Pessimism: 25%
Bullish for Stocks

Smart Money / Dumb Money Confidence Spread
Smart Money Confidence
Inverse ETF Volume
S&P 500 Price Oscillator
S&P 500 Down Pressure
Short-term Optimism Index (Optix)
Dumb Money Confidence
Intermediate Term Optimism Index (Optix)
VIX
NYSE High/Low Ratio
Rydex Sector Breadth
AAII Bull Ratio
SPY Liquidity Premium
Equity Put/Call Ratio De-Trended
Risk Appetite Index
Mutual Fund Flow (no ETFs)
% Showing Optimism: 28%
Bearish for Stocks

VIX Term Structure
Rydex Money Market %
Rydex Ratio
Rydex Bearish Flow
SKEW Index
CSFB Fear Barometer
OEX Open Interest Ratio
LOBO Put/Call Ratio
ROBO Put/Call Ratio
Options Speculation Index
AAII Allocation - Stocks
NYSE Available Cash
Equity / Money Market Asset Ratio
Mutual Fund Cash Level
Retail Money Market Ratio
VIX Transform

Portfolio

PositionDescriptionWeight %Added / ReducedDate
StocksRSP10.7Added 6.4%2021-10-01
Bonds32.7% BND, 7.1% SCHP39.8Added 8.3%2021-10-26
CommoditiesGCC2.4Reduced 2.1%
2020-09-04
Precious MetalsGDX4.6Reduced 4.2%2021-05-19
Special Situations9.8% KWEB, 4.7% XLE, 2.9% PSCE17.3Added 9.78%2021-10-01
Cash24.1
Updates (Changes made today are underlined)

No surprise for 2021, but we're seeing conflicting messages in some of what has developed lately. There was a jump in pessimism heading into December, which has been relieved to some degree. The subsequent breadth thrust has extremely positive implications for forward returns, especially longer-term.

The negatives are mostly sector-related, especially the negative divergences among Nasdaq 100 stocks. Consumer Staples have seen an impressive surge, and Biotech may be oversold, but otherwise there are a whole lot of crosscurrents and seemingly not much edge. 

Bond sentiment is trying to recover from a recent bout of pessimism, and gold stocks are doing their thing which is not much at all. They've been flat for six months. Chinese tech stocks were doing exactly what they're supposed to do, then did *not* by plunging to new lows. This is troubling on a shorter-term time frame, but this was never meant for a trade, rather a multi-year investment. Recent behavior is troubling and I will not be adding any exposure as long as that's the case.

RETURN YTD:  8.1%

2020: 8.1%, 2019: 12.6%, 2018: 0.6%, 2017: 3.8%, 2016: 17.1%, 2015: 9.2%, 2014: 14.5%, 2013: 2.2%, 2012: 10.8%, 2011: 16.5%, 2010: 15.3%, 2009: 23.9%, 2008: 16.2%, 2007: 7.8%

Phase Table

Click here to view the Phase Table on the site.

Ranks

Click here to view on the site (Ranks tab on the Dashboard).

Sentiment Around The World

Click here to view on the site.

Optimism Index Thumbnails

Sector ETF's - 10-Day Moving Average
Country ETF's - 10-Day Moving Average
Bond ETF's - 10-Day Moving Average
Currency ETF's - 5-Day Moving Average
Commodity ETF's - 5-Day Moving Average

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